Basic Information
ID: ALA4419150
Type: Functional
Description: Modulation activity at GPR6 receptor (unknown origin) expressed in CHO-K1 cells assessed as inhibition of constitutive cAMP activity incubated for 45 mins in presence of 300 uM IBMX by Perkin Elmer Lance HTRF Ultrac-AMP assay
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA4419150
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.51 | 4.02 | 4.02 |
| 459.54 | 3.92 | 3.92 |
| 472.58 | 3.44 | 3.44 |
| 473.52 | 2.64 | 2.64 |
| 471.55 | 3.92 | 3.92 |
| 467.51 | 4.25 | 4.25 |
| 431.49 | 3.14 | 3.14 |
| 503.52 | 2.80 | 2.80 |
| 429.54 | 3.48 | 3.48 |
| 451.55 | 2.53 | 2.53 |
| 459.54 | 4.09 | 4.09 |
| 473.52 | 2.64 | 2.64 |
| 505.62 | 2.79 | 2.79 |
| 475.59 | 2.78 | 2.78 |
| 417.50 | 3.61 | 3.61 |
| 472.54 | 2.18 | 2.18 |
| 515.56 | 3.21 | 3.21 |
| 481.57 | 2.94 | 2.94 |
| 488.58 | 4.22 | 4.22 |
| 481.49 | 3.77 | 3.77 |
| 472.54 | 1.92 | 1.92 |
| 481.57 | 2.94 | 2.94 |
| 475.59 | 2.78 | 2.78 |
| 503.45 | 3.63 | 3.63 |
| 433.52 | 4.49 | 4.49 |
| 495.52 | 4.33 | 4.33 |
| 461.51 | 3.75 | 3.75 |
| 433.52 | 4.49 | 4.49 |
| 510.54 | 4.08 | 4.08 |
| 471.55 | 3.92 | 3.92 |
| 439.46 | 3.47 | 3.47 |
| 444.53 | 2.80 | 2.80 |
| 445.51 | 3.53 | 3.53 |
| 488.58 | 4.22 | 4.22 |
| 497.49 | 3.01 | 3.01 |
| 417.50 | 3.61 | 3.61 |
| 486.57 | 2.57 | 2.57 |
| 480.59 | 2.21 | 2.21 |
| 517.47 | 4.19 | 4.19 |
| 475.54 | 3.15 | 3.15 |
| 493.51 | 3.92 | 3.92 |
| 467.47 | 3.38 | 3.38 |
| 495.52 | 4.33 | 4.33 |
| 418.54 | 2.26 | 2.26 |
| 449.52 | 3.95 | 3.95 |
| 457.53 | 3.67 | 3.67 |
| 473.52 | 2.91 | 2.91 |
| 457.55 | 3.40 | 3.40 |
| 459.54 | 3.92 | 3.92 |
| 461.53 | 4.41 | 4.41 |
| 495.60 | 3.50 | 3.50 |
| 457.55 | 3.40 | 3.40 |
| 461.51 | 3.75 | 3.75 |
| 514.62 | 3.60 | 3.60 |
| 456.54 | 2.95 | 2.95 |
| 515.56 | 3.21 | 3.21 |
| 493.58 | 3.08 | 3.08 |
| 445.51 | 3.53 | 3.53 |
| 458.56 | 3.19 | 3.19 |
| 517.47 | 4.19 | 4.19 |
| 474.53 | 2.89 | 2.89 |
| 487.55 | 3.30 | 3.30 |
| 475.59 | 2.78 | 2.78 |
| 449.52 | 3.95 | 3.95 |
| 514.58 | 2.49 | 2.49 |
| 487.63 | 2.65 | 2.65 |
| 459.54 | 3.92 | 3.92 |
| 472.54 | 2.18 | 2.18 |
| 447.51 | 4.02 | 4.02 |
| 448.53 | 3.53 | 3.53 |
| 461.53 | 4.41 | 4.41 |
| 475.54 | 3.15 | 3.15 |
| 475.54 | 3.15 | 3.15 |