Basic Information
ID: ALA4419456
Type: Binding
Description: Inhibition of GFP-tagged human ferroportin expressed in HEK293 #354 cells assessed as reduction in Fpn-mediated iron efflux incubated overnight by iron regulatory element -driven beta-lactamase reporter gene assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4419456
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 452.56 | 3.59 | 3.59 |
| 461.42 | 3.03 | 3.03 |
| 424.51 | 2.86 | 2.86 |
| 452.97 | 3.64 | 3.64 |
| 433.45 | 2.26 | 2.26 |
| 395.49 | 2.02 | 2.02 |
| 427.51 | 2.67 | 2.67 |
| 519.86 | 2.82 | 2.82 |
| 438.53 | 3.17 | 3.17 |
| 461.38 | 3.98 | 3.98 |
| 375.44 | 1.87 | 1.87 |
| 460.49 | 3.41 | 3.41 |
| 426.93 | 3.33 | 3.33 |
| 516.89 | 2.11 | 2.11 |
| 426.43 | 2.53 | 2.53 |
| 499.83 | 2.25 | 2.25 |
| 410.48 | 2.82 | 2.82 |
| 551.88 | 3.00 | 3.00 |
| 438.53 | 3.17 | 3.17 |
| 406.52 | 2.99 | 2.99 |
| 407.45 | 2.09 | 2.09 |
| 394.41 | 1.41 | 1.41 |
| 444.42 | 2.67 | 2.67 |
| 409.88 | 2.53 | 2.53 |
| 389.46 | 1.92 | 1.92 |
| 460.87 | 3.18 | 3.18 |
| 419.46 | 2.32 | 2.32 |
| 428.47 | 2.95 | 2.95 |
| 540.67 | 2.30 | 2.30 |
| 537.85 | 2.95 | 2.95 |
| 410.48 | 2.82 | 2.82 |
| 438.46 | 2.40 | 2.40 |
| 394.41 | 2.35 | 2.35 |
| 424.51 | 3.12 | 3.12 |
| 438.44 | 2.80 | 2.80 |
| 393.48 | 2.07 | 2.07 |
| 406.52 | 2.99 | 2.99 |
| 424.89 | 2.90 | 2.90 |
| 409.49 | 3.42 | 3.42 |
| 476.43 | 3.41 | 3.41 |
| 420.54 | 3.29 | 3.29 |
| 408.44 | 2.39 | 2.39 |
| 393.43 | 2.01 | 2.01 |
| 394.41 | 2.35 | 2.35 |
| 527.91 | 3.16 | 3.16 |
| 412.40 | 2.49 | 2.49 |
| 615.74 | 4.89 | 4.89 |
| 420.45 | 2.66 | 2.66 |
| 402.46 | 2.52 | 2.52 |
| 376.42 | 2.21 | 2.21 |
| 410.48 | 3.53 | 3.53 |
| 406.52 | 2.72 | 2.72 |
| 488.45 | 3.68 | 3.68 |
| 406.52 | 2.99 | 2.99 |
| 441.95 | 2.77 | 2.77 |
| 410.87 | 1.92 | 1.92 |
| 424.51 | 3.12 | 3.12 |
| 426.43 | 2.53 | 2.53 |
| 516.89 | 2.11 | 2.11 |
| 568.33 | 3.51 | 3.51 |
| 416.51 | 3.15 | 3.15 |
| 515.90 | 2.99 | 2.99 |
| 470.96 | 3.78 | 3.78 |
| 533.89 | 3.21 | 3.21 |
| 475.45 | 3.07 | 3.07 |
| 517.82 | 2.39 | 2.39 |
| 405.44 | 2.28 | 2.28 |
| 410.48 | 2.82 | 2.82 |
| 423.91 | 2.57 | 2.57 |
| 393.48 | 2.07 | 2.07 |
| 486.96 | 2.88 | 2.88 |
| 503.79 | 2.35 | 2.35 |
| 382.45 | 2.27 | 2.27 |
| 410.87 | 2.86 | 2.86 |
| 417.50 | 2.55 | 2.55 |
| 438.44 | 2.80 | 2.80 |
| 426.93 | 3.33 | 3.33 |
| 410.48 | 2.82 | 2.82 |
| 408.44 | 1.45 | 1.45 |
| 444.92 | 3.47 | 3.47 |
| 455.98 | 3.08 | 3.08 |
| 395.49 | 2.02 | 2.02 |
| 492.50 | 3.88 | 3.88 |
| 393.48 | 2.07 | 2.07 |
| 452.97 | 3.53 | 3.53 |
| 440.96 | 3.37 | 3.37 |
| 407.50 | 2.38 | 2.38 |
| 424.51 | 2.86 | 2.86 |
| 410.48 | 2.82 | 2.82 |
| 460.49 | 3.70 | 3.70 |
| 444.42 | 2.67 | 2.67 |
| 501.87 | 2.68 | 2.68 |
| 395.49 | 2.02 | 2.02 |
| 569.87 | 3.14 | 3.14 |
| 421.53 | 2.42 | 2.42 |
| 401.47 | 2.36 | 2.36 |
| 444.92 | 3.47 | 3.47 |
| 489.65 | 3.03 | 3.03 |
| 494.93 | 4.35 | 4.35 |
| 551.88 | 3.00 | 3.00 |
| 698.46 | 4.22 | 4.22 |
| 420.45 | 2.66 | 2.66 |
| 530.91 | 2.42 | 2.42 |
| 420.45 | 2.66 | 2.66 |
| 409.52 | 2.32 | 2.32 |
| 515.90 | 2.99 | 2.99 |
| 432.55 | 3.21 | 3.21 |
| 422.51 | 2.69 | 2.69 |
| 427.92 | 2.73 | 2.73 |
| 568.68 | 4.69 | 4.69 |
| 432.55 | 3.55 | 3.55 |
| 444.42 | 2.67 | 2.67 |
| 422.46 | 2.70 | 2.70 |
| 403.45 | 1.91 | 1.91 |
| 442.88 | 3.04 | 3.04 |
| 438.44 | 2.80 | 2.80 |
| 553.30 | 2.06 | 2.06 |
| 530.91 | 2.42 | 2.42 |
| 393.48 | 2.07 | 2.07 |
| 436.52 | 3.13 | 3.13 |
| 408.44 | 2.39 | 2.39 |
| 408.44 | 1.45 | 1.45 |
| 428.47 | 2.95 | 2.95 |
| 442.50 | 3.00 | 3.00 |
| 395.49 | 2.02 | 2.02 |
| 444.56 | 3.47 | 3.47 |
| 524.88 | 2.40 | 2.40 |
| 420.54 | 3.29 | 3.29 |
| 547.92 | 3.20 | 3.20 |
| 519.86 | 2.82 | 2.82 |