Basic Information
ID: ALA4419755
Type: Binding
Description: Inhibition of recombinant APOBEC3A (unknown origin) expressed in HEK293 cells assessed as reduction in cytosine deaminase activity at 200 uM using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs and measured on day 0 by fluorescence-based assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Probable DNA dC->dU-editing enzyme APOBEC-3A(ALA1741179)
Document: ALA4419174
Inhibition of recombinant APOBEC3A (unknown origin) expressed in HEK293 cells assessed as reduction in cytosine deaminase activity at 200 uM using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs and measured on day 0 by fluorescence-based assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4419755
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.46 | 4.97 | 4.97 |