Basic Information
ID: ALA4419772
Type: Binding
Description: Inhibition of recombinant APOBEC3G C321A mutant (unknown origin) expressed in HEK293 cells assessed as reduction in cytosine deaminase activity using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs by fluorescence-based assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4419772
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.38 | 2.69 | 2.69 |
| 394.37 | 2.60 | 2.60 |
| 412.27 | 4.16 | 4.16 |
| 299.31 | 1.95 | 1.95 |
| 265.23 | 0.68 | 0.68 |
| 364.39 | 2.28 | 2.28 |
| 379.40 | 2.70 | 2.70 |
| 367.82 | 4.05 | 4.05 |