Assay Report Card

Basic Information

ID: ALA4419974

Type: Functional

Description: Inhibition of self-renewal capacity in methotrexate insensitive stem-like side-population cells of human NCI-H146 cells assessed as reduction in number of spheres at 2 uM incubated for 3 days after 7 days methotrexate exposure by sphere formation assay

Organism: Homo sapiens

Cell type: NCI-H146

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
611.576.036.03
527.674.044.04
233.202.632.63
556.705.125.12
528.654.644.64
567.694.604.60