Basic Information
ID: ALA4420051
Type: Functional
Description: Inverse agonist activity at recombinant human MrgprX4 expressed in HEK293 cells assessed as reduction in inositol phosphate accumulation incubated for 1 hr at at 37 degC followed by incubation for 30 mins at room temperature by HTRF assay relative to baseline
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Mas-related G-protein coupled receptor member X4(ALA4523430)
Document: ALA4419180
Inverse agonist activity at recombinant human MrgprX4 expressed in HEK293 cells assessed as reduction in inositol phosphate accumulation incubated for 1 hr at at 37 degC followed by incubation for 30 mins at room temperature by HTRF assay relative to baseline: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4420051
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 287.75 | 3.35 | 3.35 |
| 407.82 | 4.84 | 4.84 |
| 457.33 | 5.47 | 5.47 |
| 348.84 | 4.95 | 4.95 |