Basic Information
ID: ALA4420247
Type: Binding
Description: Inhibition of RPE65 in bovine RPE microsomes assessed as reduction in isomero-hydrolase activity using all-trans-[3H]-retinol by normal phase HPLC with flow scintillation analysis
Format: BAO_0000019
Organism: Bos taurus
Target: Retinoid isomerohydrolase(ALA4523306)
Document: ALA4420061
Inhibition of RPE65 in bovine RPE microsomes assessed as reduction in isomero-hydrolase activity using all-trans-[3H]-retinol by normal phase HPLC with flow scintillation analysis: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4420247
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 177.25 | 2.41 | 2.41 |
| 191.27 | 2.72 | 2.72 |
| 213.23 | 2.69 | 2.69 |
| 207.27 | 2.42 | 2.42 |
| 213.23 | 2.69 | 2.69 |
| 195.24 | 2.55 | 2.55 |
| 279.29 | 1.66 | 1.66 |
| 195.24 | 2.55 | 2.55 |
| 195.24 | 2.55 | 2.55 |
| 221.30 | 2.81 | 2.81 |
| 245.24 | 3.43 | 3.43 |