Basic Information
ID: ALA4420249
Type: Functional
Description: Inhibition of rhodopsin regeneration in overnight dark-adaptated Sprague-Dawley rat assessed as effect on rhodopsin recovery by measuring reduction in rhodopsin content at 50 mg/kg, ip followed by exposure to room light for 2 hrs and measured 2.5 hrs after photo-bleach by spectrophotometry relative to control
Format: BAO_0000218
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Target: Rattus norvegicus(ALA376)
Document: ALA4420061
Inhibition of rhodopsin regeneration in overnight dark-adaptated Sprague-Dawley rat assessed as effect on rhodopsin recovery by measuring reduction in rhodopsin content at 50 mg/kg, ip followed by exposure to room light for 2 hrs and measured 2.5 hrs after photo-bleach by spectrophotometry relative to control: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4420249
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 177.25 | 2.41 | 2.41 |
| 191.27 | 2.72 | 2.72 |
| 195.24 | 2.55 | 2.55 |
| 245.24 | 3.43 | 3.43 |