Assay Report Card

Basic Information

ID: ALA4420252

Type: Functional

Description: Protection against light-induced retinal degeneration in overnight dark-adaptated Sprague-Dawley rat assessed as protection of retinal rod and cone function by measuring effect on A-waves at 50 mg/kg, ip dosed 30 mins prior to exposure to 400 log cd.s/m2 test flash by electroretinography relative to control

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
177.252.412.41
191.272.722.72
195.242.552.55
245.243.433.43