Basic Information
ID: ALA4420663
Type: Binding
Description: Inhibition of human LATS1 kinase domain (589 to 1130 amino acids) incubated for 1 hr in presence of Fluo-SGKtide substrate by fluorescence detection based biochemical caliper assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4420663
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.31 | 1.46 | 1.46 |
| 294.36 | 2.24 | 2.24 |
| 364.50 | 4.01 | 4.01 |
| 305.39 | 2.44 | 2.44 |
| 322.42 | 2.84 | 2.84 |
| 322.42 | 3.01 | 3.01 |
| 293.37 | 2.84 | 2.84 |
| 366.43 | 3.02 | 3.02 |
| 394.48 | 3.80 | 3.80 |
| 290.37 | 4.05 | 4.05 |
| 308.39 | 2.48 | 2.48 |
| 304.40 | 4.07 | 4.07 |
| 293.37 | 2.70 | 2.70 |
| 285.31 | 1.87 | 1.87 |
| 322.37 | 2.15 | 2.15 |
| 308.35 | 1.76 | 1.76 |
| 353.47 | 3.17 | 3.17 |
| 291.36 | 2.10 | 2.10 |
| 354.43 | 3.37 | 3.37 |
| 305.39 | 2.49 | 2.49 |
| 344.34 | 4.59 | 4.59 |
| 320.40 | 3.31 | 3.31 |
| 350.47 | 3.11 | 3.11 |
| 336.44 | 3.09 | 3.09 |
| 348.33 | 3.42 | 3.42 |
| 322.42 | 2.65 | 2.65 |
| 393.42 | 3.58 | 3.58 |
| 360.34 | 2.43 | 2.43 |
| 278.32 | 2.50 | 2.50 |
| 291.36 | 3.44 | 3.44 |
| 321.43 | 3.44 | 3.44 |
| 339.45 | 2.87 | 2.87 |
| 308.39 | 2.63 | 2.63 |
| 336.40 | 2.37 | 2.37 |
| 360.34 | 2.43 | 2.43 |
| 359.36 | 3.03 | 3.03 |
| 337.43 | 2.62 | 2.62 |
| 307.40 | 3.09 | 3.09 |
| 337.38 | 2.84 | 2.84 |
| 408.51 | 4.05 | 4.05 |
| 351.46 | 2.81 | 2.81 |
| 408.51 | 4.19 | 4.19 |
| 276.34 | 3.66 | 3.66 |
| 319.41 | 2.88 | 2.88 |
| 292.39 | 3.93 | 3.93 |