Basic Information
ID: ALA4420684
Type: Binding
Description: Inhibition of LATS in human limbal epithelial cells assessed as induction of limbal stem cell expansion by measuring measuring ratio of expanded population of cells to population of seeded cells at 10 uM measured after 2 weeks by p63alpha expression detection based immunohistochemistry
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Epithelial cell
Target: Serine/threonine-protein kinase LATS(ALA4523992)
Document: ALA4420070
Inhibition of LATS in human limbal epithelial cells assessed as induction of limbal stem cell expansion by measuring measuring ratio of expanded population of cells to population of seeded cells at 10 uM measured after 2 weeks by p63alpha expression detection based immunohistochemistry: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4420684
Activity_index
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 339.40 | 2.29 | 2.29 |
| 333.32 | 3.47 | 3.47 |
| 305.39 | 3.69 | 3.69 |
| 329.33 | 4.80 | 4.80 |
| 330.31 | 4.20 | 4.20 |
| 278.36 | 3.90 | 3.90 |
| 307.36 | 2.41 | 2.41 |
| 265.32 | 2.91 | 2.91 |
| 265.32 | 2.91 | 2.91 |
| 367.76 | 4.49 | 4.49 |
| 360.34 | 2.43 | 2.43 |
| 295.35 | 2.27 | 2.27 |
| 337.43 | 3.44 | 3.44 |
| 291.36 | 3.44 | 3.44 |
| 322.29 | 3.26 | 3.26 |
| 367.45 | 3.06 | 3.06 |
| 345.33 | 3.98 | 3.98 |
| 280.34 | 2.69 | 2.69 |