Basic Information
ID: ALA4420685
Type: Binding
Description: Inhibition of LATS in human limbal epithelial cells assessed as induction of limbal stem cell expansion by measuring p63alpha expression at 10 uM measured after 2 weeks by immunohistochemistry relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Epithelial cell
Target: Serine/threonine-protein kinase LATS(ALA4523992)
Document: ALA4420070
Inhibition of LATS in human limbal epithelial cells assessed as induction of limbal stem cell expansion by measuring p63alpha expression at 10 uM measured after 2 weeks by immunohistochemistry relative to control: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4420685
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 339.40 | 2.29 | 2.29 |
| 333.32 | 3.47 | 3.47 |
| 305.39 | 3.69 | 3.69 |
| 329.33 | 4.80 | 4.80 |
| 330.31 | 4.20 | 4.20 |
| 278.36 | 3.90 | 3.90 |
| 307.36 | 2.41 | 2.41 |
| 265.32 | 2.91 | 2.91 |
| 265.32 | 2.91 | 2.91 |
| 367.76 | 4.49 | 4.49 |
| 360.34 | 2.43 | 2.43 |
| 295.35 | 2.27 | 2.27 |
| 337.43 | 3.44 | 3.44 |
| 291.36 | 3.44 | 3.44 |
| 322.29 | 3.26 | 3.26 |
| 367.45 | 3.06 | 3.06 |
| 345.33 | 3.98 | 3.98 |
| 280.34 | 2.69 | 2.69 |