Basic Information
ID: ALA4420689
Type: Binding
Description: Inhibition of LATS in human limbal epithelial cells assessed as induction of cell differentiation into corneal epithelial cells by measuring keratin-12 expression at 10 uM incubated for 8 to 10 days followed by medium change to DMEM medium without serum and compound for further incubation for 4 to 8 days by confocal microscopy
Organism: Homo sapiens
Cell type: Epithelial cell
Activity Charts
Bioactivity
Activity Types for Assay ALA4420689
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 333.32 | 3.47 | 3.47 |
| 278.36 | 3.90 | 3.90 |
| 337.43 | 3.44 | 3.44 |
| 367.45 | 3.06 | 3.06 |