Basic Information
ID: ALA4420692
Type: Binding
Description: Inhibition of LATS in human limbal epithelial cells with CRISPR/Cas9-mediated deletion of beta-2-microglobulin gene and HLA A/B/C genes assessed as induction of cell expansion to cell preparation without HLA class-I drivers of immune rejection (Rvb = 21%)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Epithelial cell
Target: Serine/threonine-protein kinase LATS(ALA4523992)
Document: ALA4420070
Inhibition of LATS in human limbal epithelial cells with CRISPR/Cas9-mediated deletion of beta-2-microglobulin gene and HLA A/B/C genes assessed as induction of cell expansion to cell preparation without HLA class-I drivers of immune rejection (Rvb = 21%): 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4420692
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 333.32 | 3.47 | 3.47 |