Basic Information
ID: ALA4421088
Type: Binding
Description: Binding affinity to N-terminal 6x-His-tagged recombinant human SOS1 catalytic domain (residues 564 to 1049 residues) expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-terminal-GST-tagged H-Ras (1 to 166 residues) binding to NT-647 cysteine-labeled purified SOS1 catalytic domain by competitive microscale thermophoresis analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4421088
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.44 | 3.48 | 3.48 |
| 432.43 | 6.32 | 6.32 |
| 327.37 | 1.75 | 1.75 |
| 403.91 | 5.93 | 5.93 |