Assay Report Card

Basic Information

ID: ALA4421100

Type: Binding

Description: Inhibition of SOS1 in overnight serum-starved and H-RasG12V transduced mouse MEF assessed as reduction in Akt phosphorylation at 10 to 40 uM pre-incubated for 2 hrs before EGF stimulation for 5 mins by Western blot analysis

Organism: Mus musculus

Cell type: MEF

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
438.443.483.48