Basic Information
ID: ALA4421123
Type: Binding
Description: Inhibition of N-terminal 6x-His-tagged recombinant human SOS1 catalytic domain (residues 564 to 1049 residues) expressed in Escherichia coli BL21 (DE3) assessed as reduction in 50 nM SOS1-mediated GTP loading of 2 uM N-terminal-GST-tagged H-Ras (1 to 166 residues) by BODIPY-TR-GTP GTP loading exchange assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4421123
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 432.43 | 6.32 | 6.32 |
| 403.91 | 5.93 | 5.93 |