Assay Report Card

Basic Information

ID: ALA4421125

Type: Binding

Description: Inhibition of SOS1 in overnight serum-starved mouse NIH/3T3 cells assessed as effect on Ras-GTP levels at 20 to 40 uM pre-incubated for 16 hrs before EGF stimulation for 5 mins by GST-Raf1 effector domain pulldown assay

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
432.436.326.32