Basic Information
ID: ALA4421132
Type: Binding
Description: Inhibition of SOS1 in overnight serum-starved human DU145 cells assessed as reduction in ERK1 phosphorylation at 20 to 40 uM pre-incubated for 16 hrs before EGF stimulation for 5 mins by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4421132
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 432.43 | 6.32 | 6.32 |
| 403.91 | 5.93 | 5.93 |