Basic Information
ID: ALA4421140
Type: Binding
Description: Inhibition of allosteric site activation of N-terminal 6x-His-tagged recombinant human SOS1 catalytic domain (residues 564 to 1049 residues) expressed in Escherichia coli BL21 (DE3) in presence of N-terminal-GST-tagged H-Ras (1 to 166 residues) using BODIPY-fluorescein labeled GDP and GTP by fluorescence-based guanine nucleotide exchange assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4421140
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.44 | 3.48 | 3.48 |
| 327.37 | 1.75 | 1.75 |
| 325.37 | 5.72 | 5.72 |