Basic Information
ID: ALA4421144
Type: Binding
Description: Inhibition of N-terminal 6x-His-tagged recombinant human SOS1 catalytic domain (residues 564 to 1049 residues) expressed in Escherichia coli BL21 (DE3) assessed as disruption of allosteric SOS1/Ras Y64A mutant:GTPgammaS interaction by Western lot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4421144
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.44 | 3.48 | 3.48 |
| 327.37 | 1.75 | 1.75 |