Assay Report Card

Basic Information

ID: ALA4421196

Type: Functional

Description: Antitumor activity against human MDA-MB-231 cells xenografted in NCR mouse assessed as reduction in tumor growth by measuring ratio of average tumour volume between compound treated and vehicle control at 100 mg/kg, po QD up to 28 consecutive days

Organism: Homo sapiens

Cell type: MDA-MB-231

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
407.543.113.11
495.482.812.81
398.942.402.40
602.492.802.80
441.791.891.89