Basic Information
ID: ALA4421218
Type: Binding
Description: Competitive binding affinity to full-length mouse SOX18 expressed in Sf9 cells assessed as reduction in SOX1 8- DNA binding by measuring FP-bound fraction at 50 uM using FAM-labelled Prox1 -DNA element incubated for 5 mins in dark at room temperature, 10 mins at 37 degC and 30 mins at room temperature by fluorescence polarization assay relative to control
Organism: Mus musculus
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4421218
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 322.40 | 4.65 | 4.65 |
| 320.39 | 5.04 | 5.04 |
| 270.33 | 3.88 | 3.88 |
| 270.33 | 3.88 | 3.88 |
| 272.34 | 3.50 | 3.50 |
| 242.27 | 2.88 | 2.88 |
| 280.32 | 3.74 | 3.74 |
| 230.26 | 2.59 | 2.59 |
| 240.26 | 3.26 | 3.26 |
| 304.35 | 4.72 | 4.72 |
| 290.32 | 4.41 | 4.41 |
| 320.34 | 4.42 | 4.42 |
| 322.36 | 4.04 | 4.04 |
| 326.78 | 4.68 | 4.68 |
| 306.36 | 4.34 | 4.34 |
| 359.47 | 5.50 | 5.50 |
| 359.47 | 5.50 | 5.50 |
| 361.49 | 5.12 | 5.12 |
| 347.46 | 4.81 | 4.81 |
| 389.50 | 5.51 | 5.51 |
| 389.50 | 5.51 | 5.51 |
| 391.51 | 5.12 | 5.12 |
| 363.46 | 4.52 | 4.52 |
| 338.79 | 5.37 | 5.37 |
| 304.35 | 4.72 | 4.72 |
| 318.37 | 5.03 | 5.03 |
| 334.37 | 4.73 | 4.73 |
| 324.76 | 5.07 | 5.07 |
| 322.40 | 4.70 | 4.70 |
| 336.39 | 4.34 | 4.34 |