Basic Information
ID: ALA4421314
Type: Binding
Description: Inhibition of SOS1 in human MIAPaCa2 cells grown under 3D anchorage-independent soft-agar conditions at assessed as ERK1/2 phosphorylation at Thr202/Tyr204 residues at 1 uM in presence of 50 nM trametinib incubated for 2 to 8 hrs by Western blotting analysis relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Son of sevenless homolog 1(ALA2079846)
Document: ALA4420081
Inhibition of SOS1 in human MIAPaCa2 cells grown under 3D anchorage-independent soft-agar conditions at assessed as ERK1/2 phosphorylation at Thr202/Tyr204 residues at 1 uM in presence of 50 nM trametinib incubated for 2 to 8 hrs by Western blotting analysis relative to control: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4421314
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.47 | 4.89 | 4.89 |