Basic Information
ID: ALA4421331
Type: Functional
Description: Antitumor activity against human MIAPaCa2 cells grown under 3D anchorage-independent soft-agar conditions at xenografted in BomTacNMRI-Foxn1 nu mouse assessed as inhibition of tumor growth at 50 mg/kg, po BID co-treated with 10 mg/kg, iv paclitaxel dosed in q7d regime relative to control
Format: BAO_0000218
Organism: Homo sapiens
Cell type: MIA PaCa-2
Target: MIA PaCa-2(ALA614725)
Document: ALA4420081
Antitumor activity against human MIAPaCa2 cells grown under 3D anchorage-independent soft-agar conditions at xenografted in BomTacNMRI-Foxn1 nu mouse assessed as inhibition of tumor growth at 50 mg/kg, po BID co-treated with 10 mg/kg, iv paclitaxel dosed in q7d regime relative to control: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4421331
TGI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.47 | 4.89 | 4.89 |