Basic Information
ID: ALA4421800
Type: Functional
Description: Modulation activity at GPR6 receptor (unknown origin) expressed in CHO-K1 cells assessed as inhibition of constitutive cAMP activity incubated for 45 mins by Perkin Elmer Lance HTRF Ultrac-AMP assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: G-protein coupled receptor 6(ALA3714130)
Document: ALA4421718
Modulation activity at GPR6 receptor (unknown origin) expressed in CHO-K1 cells assessed as inhibition of constitutive cAMP activity incubated for 45 mins by Perkin Elmer Lance HTRF Ultrac-AMP assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4421800
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 590.48 | 4.47 | 4.47 |
| 570.52 | 5.38 | 5.38 |
| 438.46 | 4.68 | 4.68 |
| 438.46 | 4.68 | 4.68 |
| 521.93 | 4.35 | 4.35 |
| 539.92 | 4.49 | 4.49 |
| 462.36 | 4.49 | 4.49 |
| 425.90 | 4.49 | 4.49 |
| 640.59 | 4.28 | 4.28 |
| 493.51 | 3.76 | 3.76 |
| 543.38 | 4.23 | 4.23 |
| 546.94 | 3.69 | 3.69 |
| 502.54 | 3.54 | 3.54 |
| 528.46 | 3.34 | 3.34 |
| 650.99 | 4.26 | 4.26 |
| 526.92 | 3.71 | 3.71 |
| 595.41 | 4.27 | 4.27 |
| 552.92 | 3.50 | 3.50 |
| 573.92 | 3.85 | 3.85 |
| 534.44 | 3.30 | 3.30 |
| 565.48 | 3.90 | 3.90 |
| 511.46 | 2.59 | 2.59 |
| 509.48 | 4.34 | 4.34 |
| 419.43 | 4.44 | 4.44 |
| 523.51 | 4.64 | 4.64 |
| 529.44 | 4.06 | 4.06 |
| 557.91 | 4.63 | 4.63 |
| 539.92 | 4.49 | 4.49 |
| 413.45 | 4.80 | 4.80 |
| 427.47 | 5.11 | 5.11 |
| 535.47 | 4.40 | 4.40 |
| 551.49 | 5.28 | 5.28 |
| 420.47 | 4.21 | 4.21 |
| 544.47 | 5.22 | 5.22 |
| 526.48 | 5.08 | 5.08 |
| 551.49 | 5.28 | 5.28 |
| 391.48 | 3.66 | 3.66 |
| 407.91 | 4.35 | 4.35 |
| 523.46 | 3.98 | 3.98 |
| 523.46 | 3.98 | 3.98 |
| 450.40 | 4.41 | 4.41 |
| 640.59 | 4.28 | 4.28 |
| 501.55 | 4.14 | 4.14 |
| 427.51 | 2.85 | 2.85 |
| 545.46 | 4.08 | 4.08 |
| 526.92 | 3.71 | 3.71 |
| 468.97 | 3.24 | 3.24 |
| 582.99 | 3.24 | 3.24 |
| 579.41 | 5.40 | 5.40 |
| 533.50 | 4.81 | 4.81 |
| 509.92 | 4.30 | 4.30 |
| 509.92 | 4.30 | 4.30 |
| 541.50 | 5.11 | 5.11 |
| 523.51 | 4.64 | 4.64 |
| 525.48 | 4.23 | 4.23 |
| 541.50 | 5.11 | 5.11 |
| 591.46 | 5.19 | 5.19 |
| 589.36 | 5.29 | 5.29 |
| 439.49 | 5.53 | 5.53 |
| 443.45 | 4.92 | 4.92 |
| 606.37 | 5.57 | 5.57 |
| 527.47 | 4.80 | 4.80 |
| 437.49 | 4.30 | 4.30 |
| 517.51 | 3.71 | 3.71 |
| 386.46 | 3.52 | 3.52 |
| 557.91 | 4.63 | 4.63 |
| 493.51 | 3.76 | 3.76 |
| 598.55 | 4.51 | 4.51 |
| 517.51 | 3.85 | 3.85 |
| 578.37 | 5.11 | 5.11 |
| 448.55 | 2.90 | 2.90 |
| 539.51 | 4.35 | 4.35 |
| 553.51 | 5.53 | 5.53 |
| 551.49 | 5.28 | 5.28 |
| 541.50 | 5.11 | 5.11 |
| 527.49 | 3.82 | 3.82 |
| 455.48 | 4.77 | 4.77 |
| 561.91 | 5.46 | 5.46 |
| 561.91 | 5.46 | 5.46 |
| 529.47 | 3.41 | 3.41 |
| 434.93 | 3.81 | 3.81 |
| 447.89 | 5.40 | 5.40 |
| 445.46 | 5.19 | 5.19 |
| 431.44 | 4.89 | 4.89 |
| 438.46 | 4.68 | 4.68 |
| 386.46 | 3.52 | 3.52 |
| 501.51 | 4.01 | 4.01 |
| 598.55 | 4.51 | 4.51 |
| 519.52 | 3.70 | 3.70 |
| 438.46 | 4.68 | 4.68 |
| 398.47 | 3.57 | 3.57 |
| 511.45 | 3.93 | 3.93 |
| 538.96 | 3.64 | 3.64 |
| 544.91 | 3.85 | 3.85 |
| 510.47 | 3.20 | 3.20 |
| 535.50 | 3.85 | 3.85 |
| 439.49 | 5.53 | 5.53 |
| 509.48 | 4.34 | 4.34 |
| 500.48 | 3.52 | 3.52 |
| 522.50 | 3.12 | 3.12 |