Basic Information
ID: ALA4421914
Type: Binding
Description: Inhibition of rat recombinant geranylgeranyltransferase type I expressed in Escherichia coli assessed as residual enzyme activity for geranylgeranylation of RhoA at 50 uM incubated for 30 mins in presence of [3H]GGPP by scintillation counting assay relative to control
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4421914
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 502.42 | 6.19 | 6.19 |
| 522.84 | 6.53 | 6.53 |
| 467.97 | 5.54 | 5.54 |
| 516.45 | 6.50 | 6.50 |
| 502.42 | 6.19 | 6.19 |
| 536.86 | 6.84 | 6.84 |
| 581.32 | 6.95 | 6.95 |
| 485.96 | 5.68 | 5.68 |
| 536.86 | 6.84 | 6.84 |
| 459.56 | 4.18 | 4.18 |
| 536.50 | 6.30 | 6.30 |
| 417.50 | 4.31 | 4.31 |
| 482.00 | 5.84 | 5.84 |
| 591.32 | 6.41 | 6.41 |
| 433.96 | 4.82 | 4.82 |
| 512.43 | 5.65 | 5.65 |
| 540.55 | 5.74 | 5.74 |
| 546.11 | 6.04 | 6.04 |
| 552.50 | 6.00 | 6.00 |
| 543.68 | 5.92 | 5.92 |
| 495.67 | 5.18 | 5.18 |
| 622.25 | 6.88 | 6.88 |
| 499.63 | 5.27 | 5.27 |
| 656.69 | 7.53 | 7.53 |
| 566.53 | 6.14 | 6.14 |
| 530.11 | 5.83 | 5.83 |
| 534.14 | 6.33 | 6.33 |
| 580.56 | 6.63 | 6.63 |
| 530.11 | 6.10 | 6.10 |
| 484.64 | 4.63 | 4.63 |
| 526.72 | 5.94 | 5.94 |
| 546.11 | 6.04 | 6.04 |
| 525.69 | 5.18 | 5.18 |
| 482.07 | 5.39 | 5.39 |
| 561.77 | 6.09 | 6.09 |
| 509.69 | 5.48 | 5.48 |
| 594.98 | 6.55 | 6.55 |
| 539.72 | 5.57 | 5.57 |
| 530.11 | 5.83 | 5.83 |
| 481.64 | 5.30 | 5.30 |
| 532.08 | 5.49 | 5.49 |
| 526.52 | 5.50 | 5.50 |
| 509.69 | 5.48 | 5.48 |
| 494.08 | 5.55 | 5.55 |
| 568.59 | 6.98 | 6.98 |
| 526.45 | 5.95 | 5.95 |
| 574.56 | 5.94 | 5.94 |
| 540.55 | 5.89 | 5.89 |
| 580.95 | 6.41 | 6.41 |
| 447.62 | 4.59 | 4.59 |
| 516.08 | 5.79 | 5.79 |
| 466.02 | 4.77 | 4.77 |
| 516.45 | 6.50 | 6.50 |
| 567.29 | 6.64 | 6.64 |
| 523.72 | 5.74 | 5.74 |
| 542.55 | 6.59 | 6.59 |
| 608.22 | 6.57 | 6.57 |
| 527.68 | 6.22 | 6.22 |
| 565.73 | 5.58 | 5.58 |
| 550.53 | 6.44 | 6.44 |
| 517.69 | 5.82 | 5.82 |
| 516.08 | 5.79 | 5.79 |
| 516.08 | 5.79 | 5.79 |
| 510.12 | 5.96 | 5.96 |
| 541.78 | 6.80 | 6.80 |
| 581.32 | 6.95 | 6.95 |
| 602.60 | 6.36 | 6.36 |
| 557.71 | 6.31 | 6.31 |
| 530.42 | 5.78 | 5.78 |
| 536.50 | 6.30 | 6.30 |
| 550.53 | 6.44 | 6.44 |
| 502.06 | 5.65 | 5.65 |
| 546.87 | 6.30 | 6.30 |
| 550.53 | 6.44 | 6.44 |
| 546.87 | 6.30 | 6.30 |
| 496.09 | 5.63 | 5.63 |
| 502.06 | 5.65 | 5.65 |
| 536.50 | 6.30 | 6.30 |
| 530.11 | 5.83 | 5.83 |
| 495.67 | 5.44 | 5.44 |
| 518.06 | 5.35 | 5.35 |
| 532.08 | 5.65 | 5.65 |
| 526.52 | 5.35 | 5.35 |
| 525.69 | 5.18 | 5.18 |
| 510.48 | 4.88 | 4.88 |
| 536.50 | 6.30 | 6.30 |
| 541.71 | 6.61 | 6.61 |
| 516.08 | 5.79 | 5.79 |
| 546.11 | 5.80 | 5.80 |
| 513.66 | 5.32 | 5.32 |
| 521.72 | 6.43 | 6.43 |
| 536.16 | 6.72 | 6.72 |
| 485.96 | 5.68 | 5.68 |
| 602.60 | 6.44 | 6.44 |
| 560.14 | 6.19 | 6.19 |
| 502.06 | 5.65 | 5.65 |
| 516.08 | 5.95 | 5.95 |
| 550.53 | 6.44 | 6.44 |
| 530.11 | 5.83 | 5.83 |
| 485.60 | 5.13 | 5.13 |
| 642.67 | 7.22 | 7.22 |
| 502.06 | 5.65 | 5.65 |
| 518.06 | 5.35 | 5.35 |
| 554.78 | 6.70 | 6.70 |
| 502.06 | 5.65 | 5.65 |
| 507.69 | 6.04 | 6.04 |
| 580.61 | 6.83 | 6.83 |
| 546.87 | 6.30 | 6.30 |
| 485.96 | 5.68 | 5.68 |
| 511.67 | 4.88 | 4.88 |
| 534.14 | 6.33 | 6.33 |
| 570.60 | 7.38 | 7.38 |
| 539.68 | 4.90 | 4.90 |
| 594.58 | 7.09 | 7.09 |
| 460.00 | 5.35 | 5.35 |
| 560.54 | 5.90 | 5.90 |
| 508.11 | 5.94 | 5.94 |
| 525.69 | 5.18 | 5.18 |
| 605.79 | 6.36 | 6.36 |
| 516.08 | 5.79 | 5.79 |
| 538.53 | 5.66 | 5.66 |
| 572.19 | 7.59 | 7.59 |
| 546.87 | 6.30 | 6.30 |
| 620.66 | 8.56 | 8.56 |
| 546.51 | 5.75 | 5.75 |
| 461.65 | 5.04 | 5.04 |
| 622.25 | 6.88 | 6.88 |
| 532.08 | 5.49 | 5.49 |