Basic Information
ID: ALA4421915
Type: Binding
Description: Inhibition of rat recombinant geranylgeranyltransferase type I expressed in Escherichia coli assessed as reduction in geranylgeranylation of K-Ras4B incubated for 30 mins in presence of [3H]GGPP by scintillation counting assay
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4421915
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 465.62 | 4.40 | 4.40 |
| 468.40 | 5.47 | 5.47 |
| 389.45 | 3.67 | 3.67 |
| 417.50 | 4.31 | 4.31 |
| 433.96 | 4.82 | 4.82 |
| 357.86 | 3.08 | 3.08 |
| 426.32 | 4.45 | 4.45 |
| 551.77 | 7.17 | 7.17 |
| 434.54 | 4.31 | 4.31 |
| 391.88 | 3.79 | 3.79 |
| 323.41 | 2.43 | 2.43 |
| 451.52 | 5.02 | 5.02 |
| 594.58 | 7.09 | 7.09 |