Basic Information
ID: ALA4421931
Type: Binding
Description: Competitive inhibition of rat recombinant geranylgeranyltransferase type I expressed in Escherichia coli assessed as reduction in geranylgeranylation of RhoA incubated for 30 mins in presence of varying level of [3H]GGPP and fixed RhoA levels by scintillation counting assay relative to control
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4421931
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 502.42 | 6.19 | 6.19 |
| 433.96 | 4.82 | 4.82 |
| 624.20 | 4.96 | 4.96 |
| 580.15 | 4.95 | 4.95 |