Basic Information
ID: ALA4421942
Type: Binding
Description: Uncompetitive inhibition of rat recombinant geranylgeranyltransferase type I expressed in Escherichia coli assessed as reduction in geranylgeranylation of RhoA incubated for 30 mins in presence of varying level of [3H]GGPP and fixed RhoA levels by scintillation counting assay by Michaelis-Menten plot analysis
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4421942
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 502.42 | 6.19 | 6.19 |
| 433.96 | 4.82 | 4.82 |