Assay Report Card

Basic Information

ID: ALA4421966

Type: Binding

Description: Inhibition of geranylgeranyltransferase type I in HEK293 cells expressing Myc-HA-tagged Rheb-WT assessed as effect on unprenylated Rap1 accumulation at 5 to 20 uM incubated for 48 hrs by SDS-PAGE and immunoblot analysis

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
582.637.057.05