Basic Information
ID: ALA4422404
Type: Binding
Description: Inhibition of CYP2A6 in human liver microsomes assessed as reduction in CYP2A6-mediated nicotine oxidase activity using [3H]-nicotine in presence of NADPH-generating system incubated for 20 mins by TLC/radiometric assay
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4422404
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 133.19 | 1.50 | 1.50 |
| 159.19 | 1.58 | 1.58 |
| 161.23 | 2.81 | 2.81 |
| 178.24 | 1.26 | 1.26 |
| 242.12 | 2.70 | 2.70 |
| 177.25 | 2.71 | 2.71 |
| 178.24 | 1.26 | 1.26 |