Basic Information
ID: ALA4422407
Type: Binding
Description: Time dependent inhibition of CYP2A6 in human microsomes assessed as reduction in enzyme-mediated coumarin 7-hydroxylation by measuring inactivation rate constant at 0.7 to 10 times IC50 in presence of glucose-6-phosphate, glucose-6-phosphate dehydrogenase and NADPH-generating system by fluorometry
Organism: Homo sapiens
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4422407
Kinact
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 146.19 | 0.65 | 0.65 |
| 145.16 | 1.47 | 1.47 |
| 132.17 | 0.39 | 0.39 |
| 160.22 | 0.99 | 0.99 |