Basic Information
ID: ALA4422410
Type: ADME
Description: Inhibition of human CYP2E1 assessed as reduction in specific vivid-blue substrate O-dealkylation by modified PanVera vivid assay protocol based method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4422410
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 146.19 | 0.65 | 0.65 |
| 161.23 | 2.81 | 2.81 |
| 145.16 | 1.47 | 1.47 |
| 179.22 | 2.95 | 2.95 |
| 204.25 | 2.62 | 2.62 |
| 188.19 | 2.15 | 2.15 |
| 188.19 | 2.15 | 2.15 |
| 175.26 | 3.12 | 3.12 |
| 193.25 | 3.26 | 3.26 |
| 173.17 | 2.15 | 2.15 |
| 156.19 | 2.14 | 2.14 |
| 173.22 | 1.97 | 1.97 |
| 235.29 | 2.99 | 2.99 |
| 159.19 | 1.58 | 1.58 |
| 189.24 | 2.62 | 2.62 |
| 203.27 | 3.01 | 3.01 |
| 190.27 | 2.27 | 2.27 |
| 363.51 | 5.22 | 5.22 |
| 174.20 | 1.80 | 1.80 |
| 132.17 | 0.39 | 0.39 |
| 160.22 | 0.99 | 0.99 |
| 204.30 | 2.53 | 2.53 |
| 161.23 | 2.81 | 2.81 |
| 175.26 | 3.12 | 3.12 |
| 193.25 | 3.26 | 3.26 |
| 188.23 | 2.06 | 2.06 |
| 218.32 | 2.87 | 2.87 |
| 202.26 | 2.40 | 2.40 |
| 159.19 | 1.48 | 1.48 |
| 233.29 | 3.12 | 3.12 |
| 191.25 | 2.77 | 2.77 |
| 205.28 | 3.20 | 3.20 |
| 173.21 | 2.41 | 2.41 |
| 189.28 | 2.87 | 2.87 |
| 174.27 | 3.72 | 3.72 |
| 160.24 | 3.42 | 3.42 |
| 176.24 | 2.51 | 2.51 |
| 145.17 | 1.47 | 1.47 |
| 136.20 | 0.97 | 0.97 |
| 174.21 | 0.93 | 0.93 |
| 175.19 | 1.20 | 1.20 |
| 176.24 | 2.39 | 2.39 |
| 188.19 | 2.15 | 2.15 |