Basic Information
ID: ALA4422431
Type: Binding
Description: Inhibition of human CYP2A6 expressed in insect cell membranes assessed as reduction in enzyme-mediated coumarin 7-hydroxylation in presence of glucose-6-phosphate, glucose-6-phosphate dehydrogenase and NADPH-generating system by fluorometry
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4422431
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 162.24 | 1.85 | 1.85 |
| 146.19 | 0.65 | 0.65 |
| 190.63 | 2.80 | 2.80 |
| 206.25 | 3.30 | 3.30 |
| 206.23 | 2.72 | 2.72 |
| 161.23 | 2.81 | 2.81 |
| 145.16 | 1.47 | 1.47 |
| 159.19 | 1.78 | 1.78 |
| 179.22 | 2.95 | 2.95 |
| 191.25 | 2.82 | 2.82 |
| 204.25 | 2.62 | 2.62 |
| 188.19 | 2.15 | 2.15 |
| 188.19 | 2.15 | 2.15 |
| 240.13 | 3.57 | 3.57 |
| 193.25 | 3.26 | 3.26 |
| 205.28 | 3.13 | 3.13 |
| 173.17 | 2.15 | 2.15 |
| 156.19 | 2.14 | 2.14 |
| 170.22 | 2.45 | 2.45 |
| 170.22 | 2.45 | 2.45 |
| 170.22 | 2.45 | 2.45 |
| 170.22 | 2.45 | 2.45 |
| 157.18 | 1.54 | 1.54 |
| 157.18 | 1.54 | 1.54 |
| 156.19 | 2.14 | 2.14 |
| 147.14 | 0.26 | 0.26 |
| 173.22 | 1.97 | 1.97 |
| 235.29 | 2.99 | 2.99 |
| 159.19 | 1.58 | 1.58 |
| 145.16 | 1.27 | 1.27 |
| 189.24 | 2.62 | 2.62 |
| 203.27 | 3.01 | 3.01 |
| 190.27 | 2.27 | 2.27 |
| 363.51 | 5.22 | 5.22 |
| 174.20 | 1.80 | 1.80 |
| 191.25 | 2.30 | 2.30 |
| 331.38 | 4.29 | 4.29 |
| 175.19 | 1.83 | 1.83 |
| 132.17 | 0.39 | 0.39 |
| 160.22 | 0.99 | 0.99 |
| 488.55 | 6.85 | 6.85 |
| 184.24 | 2.21 | 2.21 |
| 189.28 | 3.43 | 3.43 |
| 204.30 | 2.53 | 2.53 |
| 161.23 | 2.81 | 2.81 |
| 162.22 | 2.21 | 2.21 |
| 175.26 | 3.12 | 3.12 |
| 193.25 | 3.26 | 3.26 |
| 188.23 | 2.06 | 2.06 |
| 218.32 | 2.87 | 2.87 |
| 202.26 | 2.40 | 2.40 |
| 205.28 | 3.13 | 3.13 |
| 254.15 | 3.88 | 3.88 |
| 175.26 | 3.12 | 3.12 |
| 176.24 | 2.39 | 2.39 |