Basic Information
ID: ALA4422548
Type: Binding
Description: Inhibition of GST-fused human Eya2 ED (253 to 538 residues) expressed in Escherichia coli pre-incubated for 10 mins before phosphorylated H2AX peptide substrate addition and further incubated for 40 mins by malachite green-based secondary phosphatase assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4422548
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 410.45 | 3.23 | 3.23 |
| 418.86 | 2.61 | 2.61 |
| 337.40 | 3.90 | 3.90 |
| 368.37 | 3.50 | 3.50 |
| 420.81 | 4.68 | 4.68 |
| 399.79 | 4.18 | 4.18 |
| 368.37 | 3.50 | 3.50 |
| 367.43 | 3.66 | 3.66 |
| 666.28 | 10.38 | 10.38 |
| 323.38 | 3.59 | 3.59 |
| 324.37 | 2.98 | 2.98 |
| 341.37 | 3.73 | 3.73 |
| 398.64 | 7.25 | 7.25 |