Basic Information
ID: ALA4422579
Type: Binding
Description: Inhibition of StrepTag-tagged human SARM1 TIR (561 to 724 residues) expressed in HEK293T cells assessed as reduction in NADase activity in presence of NAD+ incubated for 60 mins by HPLC analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4422579
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 121.14 | 0.79 | 0.79 |
| 107.11 | 0.89 | 0.89 |
| 450.62 | 6.70 | 6.70 |
| 122.13 | 0.18 | 0.18 |
| 290.26 | 1.92 | 1.92 |
| 559.32 | -3.28 | -3.28 |
| 137.14 | -0.24 | -0.24 |
| 267.28 | 2.93 | 2.93 |
| 291.31 | 3.28 | 3.28 |
| 275.31 | 3.58 | 3.58 |
| 342.42 | 2.71 | 2.71 |
| 246.26 | 2.79 | 2.79 |
| 236.27 | 2.94 | 2.94 |
| 275.31 | 3.58 | 3.58 |
| 303.39 | 1.45 | 1.45 |
| 303.30 | 2.61 | 2.61 |
| 262.35 | 2.37 | 2.37 |
| 261.28 | 3.27 | 3.27 |
| 541.74 | 6.74 | 6.74 |
| 332.49 | 3.94 | 3.94 |
| 399.21 | 1.23 | 1.23 |
| 322.25 | 1.96 | 1.96 |
| 352.71 | 3.16 | 3.16 |
| 121.14 | 1.28 | 1.28 |
| 138.19 | 0.72 | 0.72 |
| 666.43 | -3.32 | -3.32 |