Basic Information
ID: ALA4422583
Type: Binding
Description: Inhibition of SARM1 in CD1 mouse DRG cells assessed as inhibition of axon degeneration by measuring reduction in NAD+ consumption rate added 30 mins prior to D4-Nam addition and measured 4 hrs post D4-Nam addition by LC-MS/MS analysis
Format: BAO_0000219
Organism: Mus musculus
Strain: CD1
Target: NAD(+) hydrolase SARM1(ALA4523348)
Document: ALA4421736
Inhibition of SARM1 in CD1 mouse DRG cells assessed as inhibition of axon degeneration by measuring reduction in NAD+ consumption rate added 30 mins prior to D4-Nam addition and measured 4 hrs post D4-Nam addition by LC-MS/MS analysis: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4422583
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 322.25 | 1.96 | 1.96 |