Basic Information
ID: ALA4422593
Type: Binding
Description: Inhibition of StrepTag-tagged human SARM1 TIR (561 to 724 residues) expressed in NRK1-HEK293T cells assessed as reduction in NADase activity by measuring ADPR production at 150 uM pre-incubated up to 120 mins before NAD+ addition and further incubated for 60 mins by HPLC analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4422593
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 353.37 | 4.50 | 4.50 |
| 346.41 | 2.29 | 2.29 |
| 383.39 | 3.82 | 3.82 |
| 368.39 | 2.29 | 2.29 |
| 385.37 | 3.18 | 3.18 |
| 359.45 | 2.91 | 2.91 |