Basic Information
ID: ALA4422854
Type: Binding
Description: Mixed type inhibition of human wild-type full length SHP2 assessed as Kcat/Km ratio at 20 uM using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-ProPro-Asp-Pro-Ala-Lys as substrate by Lineweaver-Burk plot analysis (Rvb = 100.3 +/- 25 /mM/sec)
Format: BAO_0000357
Organism: Homo sapiens
Target: Protein-tyrosine phosphatase 2C(ALA3864)
Document: ALA4422612
Mixed type inhibition of human wild-type full length SHP2 assessed as Kcat/Km ratio at 20 uM using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-ProPro-Asp-Pro-Ala-Lys as substrate by Lineweaver-Burk plot analysis (Rvb = 100.3 +/- 25 /mM/sec): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4422854
Kcat/Km
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 564.47 | 6.38 | 6.38 |