Assay Report Card

Basic Information

ID: ALA4422981

Type: ADME

Description: Activation of PXR in human HepG2 cells assessed as induction of CYP3A4 expression at 2 x 10'-9 to 50 x 10'-6 mol/L by luciferase reporter gene assay relative to control

Organism: Homo sapiens

Cell type: HepG2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
370.472.952.95
433.452.102.10