Basic Information
ID: ALA4423275
Type: Binding
Description: Inhibition of ABCG2 (unknown origin) expressed in MDCK II BCRP cells assessed as effect on pheophorbide A accumulation after 120 mins by flow cytometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4423275
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 344.36 | 3.32 | 3.32 |
| 214.22 | 2.88 | 2.88 |
| 230.29 | 3.35 | 3.35 |
| 214.22 | 2.88 | 2.88 |
| 292.26 | 4.31 | 4.31 |
| 533.53 | 4.31 | 4.31 |
| 517.49 | 4.17 | 4.17 |
| 458.43 | 4.18 | 4.18 |
| 503.51 | 4.30 | 4.30 |
| 419.46 | 4.33 | 4.33 |
| 471.51 | 5.06 | 5.06 |
| 473.48 | 4.29 | 4.29 |
| 447.87 | 4.92 | 4.92 |
| 449.41 | 4.55 | 4.55 |
| 407.42 | 4.21 | 4.21 |
| 413.43 | 4.27 | 4.27 |
| 554.00 | 6.50 | 6.50 |
| 588.44 | 7.16 | 7.16 |
| 451.91 | 5.27 | 5.27 |
| 503.51 | 4.30 | 4.30 |
| 505.52 | 4.03 | 4.03 |
| 507.54 | 4.64 | 4.64 |
| 451.43 | 4.28 | 4.28 |
| 413.43 | 4.27 | 4.27 |
| 485.54 | 5.45 | 5.45 |
| 443.46 | 4.28 | 4.28 |
| 519.55 | 5.85 | 5.85 |
| 447.49 | 4.63 | 4.63 |
| 445.47 | 4.02 | 4.02 |
| 473.48 | 4.29 | 4.29 |
| 453.44 | 4.90 | 4.90 |
| 457.48 | 4.67 | 4.67 |
| 431.42 | 4.41 | 4.41 |
| 443.46 | 4.28 | 4.28 |
| 459.50 | 4.41 | 4.41 |
| 477.51 | 4.63 | 4.63 |
| 403.39 | 3.86 | 3.86 |
| 427.41 | 4.15 | 4.15 |
| 330.38 | 4.87 | 4.87 |
| 433.44 | 4.21 | 4.21 |
| 364.83 | 5.52 | 5.52 |
| 268.31 | 3.69 | 3.69 |
| 230.29 | 3.35 | 3.35 |
| 435.48 | 5.94 | 5.94 |
| 457.44 | 4.16 | 4.16 |
| 461.86 | 4.80 | 4.80 |
| 451.48 | 5.64 | 5.64 |
| 511.53 | 5.66 | 5.66 |
| 464.32 | 5.55 | 5.55 |
| 314.34 | 3.31 | 3.31 |
| 481.50 | 5.65 | 5.65 |
| 399.27 | 6.17 | 6.17 |
| 487.46 | 4.17 | 4.17 |
| 480.31 | 5.25 | 5.25 |
| 296.37 | 4.47 | 4.47 |
| 417.37 | 3.74 | 3.74 |
| 441.44 | 4.46 | 4.46 |
| 282.34 | 4.08 | 4.08 |
| 260.24 | 3.57 | 3.57 |