Basic Information
ID: ALA4423277
Type: Binding
Description: Inhibition of ABCB1 in human A2780/ADR cells preincubated for 30 mins followed by calcein AM addition and measured every 60 secs for 1 hr by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4423277
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 517.49 | 4.17 | 4.17 |
| 503.51 | 4.30 | 4.30 |
| 427.41 | 4.15 | 4.15 |
| 433.44 | 4.21 | 4.21 |
| 435.48 | 5.94 | 5.94 |
| 457.44 | 4.16 | 4.16 |
| 461.86 | 4.80 | 4.80 |
| 451.48 | 5.64 | 5.64 |
| 511.53 | 5.66 | 5.66 |
| 464.32 | 5.55 | 5.55 |
| 481.50 | 5.65 | 5.65 |
| 487.46 | 4.17 | 4.17 |
| 480.31 | 5.25 | 5.25 |
| 417.37 | 3.74 | 3.74 |
| 441.44 | 4.46 | 4.46 |