Basic Information
ID: ALA4423280
Type: Binding
Description: Inhibition of ABCG2 (unknown origin) expressed in MDCK2 cells co-expressing BCRP (unknown origin) assessed as potentiation of SN-38-induced cytotoxicity measured after 72 hrs by MTT assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4423280
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 344.36 | 3.32 | 3.32 |
| 376.21 | 3.86 | 3.86 |
| 421.50 | 4.82 | 4.82 |
| 413.43 | 4.27 | 4.27 |
| 505.52 | 4.03 | 4.03 |
| 507.54 | 4.64 | 4.64 |
| 447.49 | 4.63 | 4.63 |
| 453.44 | 4.90 | 4.90 |
| 435.48 | 5.94 | 5.94 |
| 461.86 | 4.80 | 4.80 |
| 451.48 | 5.64 | 5.64 |
| 481.50 | 5.65 | 5.65 |
| 282.34 | 4.08 | 4.08 |