Basic Information
ID: ALA4423297
Type: ADME
Description: Intrinsic clearance in human hepatocytes assessed per million cells at 1 uM measured up to 120 mins in presence of NADPH by LC-MS/MS analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Hepatocyte
Target: ADMET(ALA612558)
Document: ALA4422622
Intrinsic clearance in human hepatocytes assessed per million cells at 1 uM measured up to 120 mins in presence of NADPH by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4423297
CLH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 399.38 | 1.70 | 1.70 |
| 401.81 | 1.95 | 1.95 |
| 457.46 | 2.49 | 2.49 |
| 389.41 | 2.00 | 2.00 |
| 468.53 | 4.07 | 4.07 |
| 449.39 | 2.58 | 2.58 |
| 381.39 | 1.56 | 1.56 |
| 403.34 | 1.58 | 1.58 |
| 415.83 | 2.21 | 2.21 |
| 443.48 | 2.45 | 2.45 |
| 477.51 | 2.05 | 2.05 |
| 399.38 | 1.70 | 1.70 |
| 399.38 | 1.58 | 1.58 |
| 457.91 | 3.15 | 3.15 |
| 429.86 | 2.52 | 2.52 |
| 385.35 | 1.44 | 1.44 |
| 395.42 | 1.87 | 1.87 |
| 406.40 | 1.43 | 1.43 |
| 421.41 | 0.85 | 0.85 |
| 415.83 | 2.21 | 2.21 |
| 400.82 | 1.99 | 1.99 |
| 455.49 | 2.90 | 2.90 |
| 430.48 | 2.17 | 2.17 |
| 407.42 | 1.33 | 1.33 |
| 413.41 | 2.09 | 2.09 |
| 420.42 | 1.61 | 1.61 |
| 460.28 | 2.32 | 2.32 |
| 425.42 | 2.32 | 2.32 |
| 399.38 | 2.43 | 2.43 |
| 397.41 | 2.25 | 2.25 |