Assay Report Card

Basic Information

ID: ALA4423306

Type: ADME

Description: Induction of hyperkalemia in Sprague-Dawley rat fed on low salt diet for 72 hrs assessed as increase in eplerenone-mediated Na+/K+ ratio in urine administered via oral gavage co-administered with after 8 hrs

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
415.832.212.21
342.332.582.58