Basic Information
ID: ALA4423437
Type: Functional
Description: Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as calcium flux preincubated for 142 secs followed by agonist addition and measured after 120 secs by Fluo-4-AM-dye based fluorescence assay relative to L-AP4 (minimum)
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4423437
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.34 | 3.44 | 3.44 |
| 344.80 | 3.55 | 3.55 |
| 484.43 | 5.01 | 5.01 |
| 448.40 | 4.22 | 4.22 |
| 462.43 | 4.61 | 4.61 |
| 422.41 | 4.23 | 4.23 |
| 394.35 | 3.80 | 3.80 |
| 464.44 | 4.85 | 4.85 |
| 442.37 | 3.81 | 3.81 |
| 440.40 | 4.37 | 4.37 |
| 476.46 | 5.00 | 5.00 |
| 450.42 | 4.46 | 4.46 |