Basic Information
ID: ALA4423789
Type: Binding
Description: Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and NADPH addition and measured after 60 mins by resazurin dye based diaphorase-coupled assay
Organism: Toxoplasma gondii
Activity Charts
Bioactivity
Activity Types for Assay ALA4423789
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.32 | 1.26 | 1.26 |
| 248.72 | 2.52 | 2.52 |
| 369.43 | 2.74 | 2.74 |
| 454.45 | 0.27 | 0.27 |
| 346.44 | 2.63 | 2.63 |
| 310.41 | 1.84 | 1.84 |
| 354.34 | 1.87 | 1.87 |
| 304.79 | 1.62 | 1.62 |
| 360.47 | 2.94 | 2.94 |
| 347.43 | 2.03 | 2.03 |
| 304.79 | 1.62 | 1.62 |
| 348.41 | 1.42 | 1.42 |
| 348.41 | 1.42 | 1.42 |
| 378.44 | 1.43 | 1.43 |
| 347.43 | 2.03 | 2.03 |
| 284.37 | 1.28 | 1.28 |
| 338.34 | 1.99 | 1.99 |
| 362.44 | 1.73 | 1.73 |
| 346.44 | 2.63 | 2.63 |
| 304.79 | 1.62 | 1.62 |
| 300.37 | 0.98 | 0.98 |
| 284.37 | 1.28 | 1.28 |
| 388.48 | 2.30 | 2.30 |
| 346.44 | 2.63 | 2.63 |
| 270.34 | 0.97 | 0.97 |
| 284.37 | 1.28 | 1.28 |
| 348.41 | 1.42 | 1.42 |
| 374.49 | 3.20 | 3.20 |
| 348.41 | 1.42 | 1.42 |
| 347.43 | 2.03 | 2.03 |
| 416.41 | 2.44 | 2.44 |