Basic Information
ID: ALA4424181
Type: Binding
Description: Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelled GSK3162232A as substrate measured every 30 secs intervals for 5 mins by Rhodamine110 dye-based fluorescence assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4424181
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 269.30 | 2.24 | 2.24 |
| 385.30 | 1.63 | 1.63 |
| 261.29 | 0.92 | 0.92 |
| 365.77 | 2.59 | 2.59 |
| 293.33 | 2.11 | 2.11 |
| 319.29 | 2.07 | 2.07 |
| 260.30 | 0.44 | 0.44 |
| 319.29 | 2.07 | 2.07 |
| 285.30 | 1.94 | 1.94 |
| 403.74 | 2.58 | 2.58 |
| 301.30 | 1.93 | 1.93 |
| 335.79 | 2.33 | 2.33 |
| 315.33 | 2.24 | 2.24 |
| 349.32 | 2.08 | 2.08 |
| 316.32 | 0.92 | 0.92 |