Basic Information
ID: ALA4424269
Type: Binding
Description: Antagonist activity at GAL4-VP16-fused MOR (unknown origin) expressed in human U2OS cells assessed as inhibition of DAMGO-induced beta-arrestin migration preincubated for 30 mins followed by agonist addition and measured after 3 hrs by PathHunter assay
Organism: Homo sapiens
Cell type: U2OS
Activity Charts
Bioactivity
Activity Types for Assay ALA4424269
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.52 | 2.22 | 2.22 |
| 412.33 | 2.49 | 2.49 |
| 421.55 | 3.75 | 3.75 |
| 453.56 | 4.34 | 4.34 |
| 407.52 | 3.64 | 3.64 |
| 407.52 | 3.50 | 3.50 |
| 439.54 | 4.03 | 4.03 |
| 407.52 | 3.50 | 3.50 |
| 439.54 | 3.95 | 3.95 |
| 421.55 | 3.89 | 3.89 |
| 371.49 | 2.61 | 2.61 |
| 421.55 | 3.89 | 3.89 |
| 393.54 | 4.37 | 4.37 |
| 377.49 | 3.87 | 3.87 |
| 407.56 | 4.76 | 4.76 |
| 425.51 | 3.64 | 3.64 |
| 379.51 | 4.12 | 4.12 |
| 391.52 | 4.12 | 4.12 |
| 453.56 | 4.34 | 4.34 |
| 439.54 | 3.95 | 3.95 |
| 425.51 | 3.64 | 3.64 |
| 421.55 | 3.89 | 3.89 |
| 435.57 | 4.02 | 4.02 |
| 439.54 | 4.03 | 4.03 |
| 439.54 | 4.03 | 4.03 |
| 453.56 | 4.34 | 4.34 |